Psilocybin-assisted therapy may help reduce excessive alcohol consumption.

New research shows that psychedelic drugs like psilocybin combined with psychotherapy may help treat individuals with alcohol use disorder.

• Currently, approved medications for alcohol dependence or alcohol use disorder are only modestly effective, and there is a need for newer, more effective medications.
  
  
• A small randomized clinical trial shows that administering the psychedelic drug psilocybin in combination with psychotherapy reduced the number of days of binge drinking in individuals with alcohol use disorder.
  
  
• Two doses of psilocybin administered 4 weeks apart resulted in a sustained decrease in alcohol consumption that lasted at least 28 weeks after the last dose.
  
  
• Psilocybin, therefore, shows promise for the treatment of alcohol use disorder, but more research is needed to determine the duration of its effects and the appropriate dosage.

A recent study published in JAMA Psychiatry (Trusted Source) The study showed that psilocybin therapy, in addition to psychotherapy, reduced the number of days of binge drinking and the average daily alcohol consumption in individuals with Alcohol use disorder (Trusted source) compared with an antihistamine placebo and psychotherapy.

This is the first randomized controlled trial (RCT) to show that psilocybin can help reduce excessive alcohol consumption in individuals with alcohol use disorder.

https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2795625

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